Pre-Sterile Ampoule Filling Sealing Machine

Name: Pre-Sterile Ampoule Filling Sealing Machine
Brand: Lodha International LLP
Availability: InStock

To fill and seal type D pre-sterilized closed ampoules, one needs a pre-sterile ampoule filling machine. This Monoblock machine is well-known for its dependable operation and minimal maintenance requirements; it is equipped with an unscrambler, flushing, filling, and sealing functions. An apparatus with the "No Ampoule-No Filling System" specification. The ampoule filling equipment we offer can handle production-scale ampoules with ease.

The chemical, pharmaceutical, cosmetic, veterinary, and biotech industries all make extensive use of this machine. Our Ampoule Filling and Sealing Machines are designed to meet both our standard models and the special requirements of our customers.

Characteristics
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Technical Specification
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Slim GMP layout for optimal space utilization.
Apt for use in filling and sealing ampoules of type 'D'.
Constructed from Stainless Steel 304 for non-contact components and high-quality Stainless Steel 316L for all contact parts.
Minimal component size change accommodates ampoules from 1 ml to 10 ml.
"No Ampoule - No Filling" paradigm to ensure operational efficiency.
Maintains the ampoule's center during filling and gas flushing.
Nitrogen gas flushing is possible before, during, and after filling.
Easy maintenance enabled by full accessibility.
Features a pre-warming station for optimal product handling.
Very low wear and tear with easy upkeep and cleaning requirements.

The machine's slant hopper is designed to accept pre-sterilized D-type ampoule trays. The magazine-style cassette can hold one, two, four, six, or eight closed ampoules on an eccentric ampoule rack that moves. The ampoules are heated by the intense gas pressure as the lever that turns them turns. One way to open an ampoule is to pre-heat it and then use the gas pressure (LPG + oxygen) to open it. Ampoule opening, pre-gassing, filling, post-gassing, pre-heating, and final sealing are all accomplished during the rack standstill in sequential order. Without the need for manual handling, filled and sealed ampoules are automatically gathered in an upright stainless-steel tray.

Model	LI-AFS 1C	LI-AFS 2C	LI-AFS 4C	LI-AFS 6C
No. of Head	Single	Two	Four	Six
Direction of Movement	Left to Right	Left to Right	Left to Right	Left to Right
Ampoule Handling Range	1 ml to 10 ml	1 ml to 20 ml	1 ml to 5 ml	1 ml to 5 ml
Production Output	15 to 30 ampoules/minute	30 to 55 ampoules/minute	55 to 100 ampoules/minute	100 to 150 ampoules/minute
Filling Accuracy	± 1%	± 1%	± 1%	± 1%
Required Gas for Sealing	LPG & Oxygen (O₂)	LPG & Oxygen (O₂)	LPG & Oxygen (O₂)	LPG & Oxygen (O₂)
Nitrogen Pressure Required	1 Kg/cm²	1 Kg/cm²	1 Kg/cm²	1 Kg/cm²
Oxygen Pressure Required	1 Kg/cm²	1 Kg/cm²	1 Kg/cm²	1 Kg/cm²
LPG Pressure Required	0.5 Kg/cm²	0.5 Kg/cm²	0.5 Kg/cm²	0.5 Kg/cm²
Power Specification	0.5 H.P	1 H.P.	1 H.P.	1 H.P.
Electrical Characteristics	230 Volts, Single Phase, 50 Hertz, 4 Wire System	230 Volts, Single Phase, 50 Hertz, 4 Wire System	230 Volts, Single Phase, 50 Hertz, 4 Wire System	230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts	Made from Stainless Steel 316L	Made from Stainless Steel 316L	Made from Stainless Steel 316L	Made from Stainless Steel 316L
Non-Contact Parts	Made from Stainless Steel 304	Made from Stainless Steel 304	Made from Stainless Steel 304	Made from Stainless Steel 304
Overall Dimension	915mm (L) x 610mm (W) x 965mm (H)	915mm (L) x 760mm (W) x 965mm (H)	1200mm (L) x 1070mm (W) x 965mm (H)	1200mm (L) x 1070mm (W) x 965mm (H)

* Specification can be changed as per customers’ requirements

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Industries We Serve

Certified & compliant pharmaceutical machinery

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ISO 9001:2015
Quality Management
CE Marking
European Conformity
cGMP Compliant
WHO-GMP Standards
100+ Countries
Globally Exported

Frequently Asked Questions

Common questions about Pre-Sterile Ampoule Filling Sealing Machine

Pre-Sterile Ampoule Filling Sealing Machine is a sterile/aseptic-compatible machine used in injectable pharmaceutical manufacturing. Manufactured by Lodha International LLP in Ahmedabad, Gujarat, India, it is built with SS 316L stainless-steel contact parts to cGMP, WHO-GMP and CE-compliant specifications and is used worldwide in injectable pharmaceutical, parenteral, biologics and sterile drug manufacturing applications.

Pre-Sterile Ampoule Filling Sealing Machine is used across injectable pharmaceutical, parenteral, biologics and sterile drug manufacturing. It is also routinely supplied to contract manufacturers, government labs and turnkey facility projects. View our global client list spanning 100+ countries.

The Pre-Sterile Ampoule Filling Sealing Machine is priced on a per-project basis, typically ranging from ₹50,000 for entry-level semi-automatic models to ₹50 lakh+ for fully automatic, high-speed configurations. Final price depends on capacity (output per hour), automation level, container size, head count, materials of construction and destination country. Request a free quote for accurate pricing.

Capacity ranges typically from 1,200 to 12,000 units/hour depending on configuration, container size, viscosity and number of heads. Lodha designs sterile injectable filling lines for vials, ampoules and infusion bottles from bench-scale R&D throughput to fully automatic commercial output. Specific BPM (bottles per minute) figures are confirmed at quotation stage.

Yes — Lodha International LLP builds the Pre-Sterile Ampoule Filling Sealing Machine to cGMP, WHO-GMP and CE-marked standards, with optional 21 CFR Part 11 software compliance for the HMI/PLC. All product-contact surfaces use SS 316L stainless steel, and complete IQ / OQ / PQ validation documentation is supplied on request. The company itself is ISO 9001:2015 certified.

Standard manufacturing lead time is 8 to 14 weeks from confirmed order, plus 2 to 6 weeks for international shipping depending on destination. Urgent orders can sometimes be expedited to 5–7 weeks at additional cost. Country-specific certification (EU CE, US FDA, ANVISA) may add 2 to 4 weeks.

Yes — the Pre-Sterile Ampoule Filling Sealing Machine is exported to 100+ countries across Asia, the Middle East, Africa, Europe, the Americas and Oceania. Lodha handles complete export documentation, packing, freight forwarding, customs liaison and on-site installation in the destination country. See the turnkey projects page for delivered references.

On-site installation, commissioning, IQ / OQ / PQ qualification, operator training and preventive maintenance are included for every Pre-Sterile Ampoule Filling Sealing Machine delivery. Remote troubleshooting is available 24/7 by phone, email and video. Spare parts are stocked at the Ahmedabad HQ and air-shipped within 5–7 working days to any export destination. A 12-month manufacturing warranty applies.

Countries We Export to

About Us

Our company offers complete packaging lines and processing equipment used in the production, quality control and formulation labs of pharmaceutical, dietary supplements, food, cosmetic and chemical industries. We offer a full range from production scale to small batch manufacturing equipment ideal for liquids, injectables, tablets, capsules, powders, creams and ointments.

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+91 7435031331

info@lodhapharma.com

Pre-Sterile Ampoule Filling Sealing Machine