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Pre-Sterile Ampoule Filling Sealing Machine

Pre-Sterile Ampoule Filling Sealing Machine

To fill and seal type D pre-sterilized closed ampoules, one needs a pre-sterile ampoule filling machine. This Monoblock machine is well-known for its dependable operation and minimal maintenance requirements; it is equipped with an unscrambler, flushing, filling, and sealing functions. An apparatus with the "No Ampoule-No Filling System" specification. The ampoule filling equipment we offer can handle production-scale ampoules with ease.

The chemical, pharmaceutical, cosmetic, veterinary, and biotech industries all make extensive use of this machine. Our Ampoule Filling and Sealing Machines are designed to meet both our standard models and the special requirements of our customers.

  • Characteristics
  • Procedure
  • Technical Specification
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  • Slim GMP layout for optimal space utilization.
  • Apt for use in filling and sealing ampoules of type 'D'.
  • Constructed from Stainless Steel 304 for non-contact components and high-quality Stainless Steel 316L for all contact parts.
  • Minimal component size change accommodates ampoules from 1 ml to 10 ml.
  • "No Ampoule - No Filling" paradigm to ensure operational efficiency.
  • Maintains the ampoule's center during filling and gas flushing.
  • Nitrogen gas flushing is possible before, during, and after filling.
  • Easy maintenance enabled by full accessibility.
  • Features a pre-warming station for optimal product handling.
  • Very low wear and tear with easy upkeep and cleaning requirements.

The machine's slant hopper is designed to accept pre-sterilized D-type ampoule trays. The magazine-style cassette can hold one, two, four, six, or eight closed ampoules on an eccentric ampoule rack that moves. The ampoules are heated by the intense gas pressure as the lever that turns them turns. One way to open an ampoule is to pre-heat it and then use the gas pressure (LPG + oxygen) to open it. Ampoule opening, pre-gassing, filling, post-gassing, pre-heating, and final sealing are all accomplished during the rack standstill in sequential order. Without the need for manual handling, filled and sealed ampoules are automatically gathered in an upright stainless-steel tray.

Model LI-AFS 1C LI-AFS 2C LI-AFS 4C LI-AFS 6C
No. of Head Single Two Four Six
Direction of Movement Left to Right Left to Right Left to Right Left to Right
Ampoule Handling Range 1 ml to 10 ml 1 ml to 20 ml 1 ml to 5 ml 1 ml to 5 ml
Production Output 15 to 30 ampoules/minute 30 to 55 ampoules/minute 55 to 100 ampoules/minute 100 to 150 ampoules/minute
Filling Accuracy ± 1% ± 1% ± 1% ± 1%
Required Gas for Sealing LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Pressure Required 1 Kg/cm² 1 Kg/cm² 1 Kg/cm² 1 Kg/cm²
Oxygen Pressure Required 1 Kg/cm² 1 Kg/cm² 1 Kg/cm² 1 Kg/cm²
LPG Pressure Required 0.5 Kg/cm² 0.5 Kg/cm² 0.5 Kg/cm² 0.5 Kg/cm²
Power Specification 0.5 H.P 1 H.P. 1 H.P. 1 H.P.
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Non-Contact Parts Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304
Overall Dimension 915mm (L) x 610mm (W) x 965mm (H) 915mm (L) x 760mm (W) x 965mm (H) 1200mm (L) x 1070mm (W) x 965mm (H) 1200mm (L) x 1070mm (W) x 965mm (H)

* Specification can be changed as per customers’ requirements

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Certified & Compliant Pharmaceutical Machinery

ISO 9001:2015
Quality Management
CE Marking
European Conformity
cGMP Compliant
WHO-GMP Standards
100+ Countries
Globally Exported

Frequently Asked Questions

Common questions about Pre-Sterile Ampoule Filling Sealing Machine

The price of Pre-Sterile Ampoule Filling Sealing Machine depends on the model, capacity, and specifications required. Contact Lodha International LLP directly for the best price quote tailored to your production needs. We offer competitive pricing with complete after-sales support.

Yes, Lodha International LLP exports Pre-Sterile Ampoule Filling Sealing Machine to over 100 countries worldwide, including markets in Africa, Southeast Asia, the Middle East, Europe, and the Americas. We handle complete export documentation and logistics support.

Yes, all machines including Pre-Sterile Ampoule Filling Sealing Machine are manufactured in full compliance with cGMP (current Good Manufacturing Practices) and WHO-GMP standards. Product contact parts are made from SS 316L stainless steel. Complete validation documentation (IQ/OQ/PQ) is available on request.

Standard delivery time for Pre-Sterile Ampoule Filling Sealing Machine is 8–14 weeks from order confirmation, depending on model complexity and customization requirements. Expedited production may be available for urgent requirements — please contact us to discuss your timeline.

Yes, Lodha International LLP provides complete after-sales support including installation, commissioning, operator training, and preventive maintenance services for Pre-Sterile Ampoule Filling Sealing Machine. Our engineers are available for on-site support globally.

Countries We Export to

United States | Canada | Mexico | Brazil | Argentina | Chile | Colombia | Peru | Germany | United Kingdom | France | Italy | Spain | Netherlands | Belgium | Switzerland | Sweden | Austria | Denmark | Norway | Poland | Finland | Czech Republic | Hungary | Portugal | Ireland | Greece | Slovakia | Romania | Bulgaria | China | Japan | India | South Korea | Indonesia | Vietnam | Thailand | Malaysia | Philippines | Singapore | Bangladesh | Pakistan | Saudi Arabia | United Arab Emirates | Israel | Turkey | Iran | Qatar | Kuwait | South Africa | Nigeria | Egypt | Algeria | Morocco | Kenya | Ghana | Tunisia | Australia | New Zealand | Russia | Ukraine | Belarus | Kazakhstan | Taiwan | Hong Kong | South Sudan | Uzbekistan | Oman | Jordan | Bahrain | Sri Lanka | Myanmar | Lebanon | Mongolia | Ethiopia | Libya | Angola | Zambia | Zimbabwe | Mozambique | Ivory Coast | Senegal | Uganda | Tanzania | Botswana | Ecuador | Venezuela | Bolivia | Paraguay | Uruguay | Trinidad and Tobago | Panama | Guatemala | Costa Rica | Honduras | El Salvador | Nicaragua | Dominican Republic | Haiti | Cuba

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