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Closed Ampoule Filling and Sealing Machine

Closed Ampoule Filler and Sealer Machine

Lodha Machine is a top manufacturer of machines that fill and seal closed ampoules. These machines are important in industries like pharmaceuticals, biotech, cosmetics, and more. They're designed to handle type D pre-sterilized closed ampoules perfectly. Our machines include features like placing ampoules, cleaning them, filling them accurately, and sealing them securely. We also have a special system that makes sure us to only fill ampoules that are properly in place, which prevents errors and maintains quality.

We offer both standard models and can also customize machines to fit specific needs. Our focus is on creating quality equipment that helps businesses in these industries run smoothly and meet their production goals effectively. Lodha Machine is committed to innovation and quality, making us a trusted choice for companies looking for advanced solutions in ampoule packaging technology.

  • Features
  • Process Operation
  • Technical Specification
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  • It's a small and clean machine that follows GMP (good manufacturing practices)
  • It works with a specific type of ampoule called 'D' ampoules
  • The parts that touch the medicine are made from high-quality stainless steel, while other parts are made from a different type of stainless steel
  • It can easily switch between filling different sizes of ampoules
  • The ampoule has to be placed before the machine can fill a bottle
  • It makes sure the ampoule is in the right position for filling and sealing
  • It can use nitrogen gas to keep the medicine fresh during the process
  • It's easy to access for maintenance and cleaning
  • The machine has a pre-warming station to prepare for filling
  • It's quick to switch between different tasks, needs little maintenance, and is easy to clean

The Closed Ampoule Filling and Sealing Machine is a sophisticated piece of equipment that is designed to handle the entire process of filling and sealing pre-sterilized D type ampoules. The machine starts by loading the ampoules into a slant hopper, which then transfers them onto a rotating rack. Using a combination of LPG and oxygen gas pressure, the machine heats and opens the ampoules, preparing them for filling with the desired substance. Once filled, the ampoules undergo post-gassing, pre-heating, and final sealing stages.

After this process, the machine makes sure that the ampoules are correctly positioned and handles them without any need for human touch. After sealing, the filled ampoules are automatically collected in a stainless-steel tray, ready for further processing or packaging. By properly and safely handling the ampoules, this automated method reduces the danger of contamination.

Model LI-AFS 1C LI-AFS 2C LI-AFS 4C LI-AFS 6C
No. of Head Single Two Four Six
Direction of Movement Left to Right Left to Right Left to Right Left to Right
Ampoule Handling Range 1 ml to 10 ml 1 ml to 20 ml 1 ml to 5 ml 1 ml to 5 ml
Production Output 15 to 30(ampoules/minute) 30 to 55(ampoules/minute) 55 to 100(ampoules/minute) 100 to 150(ampoules/minute)
Filling Accuracy ± 1% ± 1% ± 1% ± 1%
Require Gas for Sealing LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Pressure Required 1 Kg. /cm2 1 Kg. /cm2 1 Kg. /cm2 1 Kg. /cm2
Oxygen Pressure Required 1 Kg. /cm2 1 Kg. /cm2 1 Kg. /cm2 1 Kg. /cm2
LPG Pressure Required 0.5 Kg. /cm2 0.5 Kg. /cm2 0.5 Kg. /cm2 0.5 Kg. /cm2
Power Specification 0.5 H. P 1 H. P 1 H. P 1 H. P
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Non-Contact Parts Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304
Overall Dimension 915mm (L) x 610mm (W) x 965mm (H) 915mm (L) x 760mm (W) x 965mm (H) 1200mm (L) x 1070mm (W) x 965mm (H) 1200mm (L) x 1070mm (W) x 965mm (H)

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

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100+ Countries Globally Exported

Frequently Asked Questions

Common questions about Closed Ampoule Filling and Sealing Machine

Closed Ampoule Filling and Sealing Machine is a sterile/aseptic-compatible machine used in injectable pharmaceutical manufacturing. Manufactured by Lodha International LLP in Ahmedabad, Gujarat, India, it is built with SS 316L stainless-steel contact parts to cGMP, WHO-GMP and CE-compliant specifications and is used worldwide in injectable pharmaceutical, parenteral, biologics and sterile drug manufacturing applications.

Closed Ampoule Filling and Sealing Machine is used across injectable pharmaceutical, parenteral, biologics and sterile drug manufacturing. It is also routinely supplied to contract manufacturers, government labs and turnkey facility projects. View our global client list spanning 100+ countries.

The Closed Ampoule Filling and Sealing Machine is priced on a per-project basis, typically ranging from ₹50,000 for entry-level semi-automatic models to ₹50 lakh+ for fully automatic, high-speed configurations. Final price depends on capacity (output per hour), automation level, container size, head count, materials of construction and destination country. Request a free quote for accurate pricing.

Capacity ranges typically from 1,200 to 12,000 units/hour depending on configuration, container size, viscosity and number of heads. Lodha designs sterile injectable filling lines for vials, ampoules and infusion bottles from bench-scale R&D throughput to fully automatic commercial output. Specific BPM (bottles per minute) figures are confirmed at quotation stage.

Yes — Lodha International LLP builds the Closed Ampoule Filling and Sealing Machine to cGMP, WHO-GMP and CE-marked standards, with optional 21 CFR Part 11 software compliance for the HMI/PLC. All product-contact surfaces use SS 316L stainless steel, and complete IQ / OQ / PQ validation documentation is supplied on request. The company itself is ISO 9001:2015 certified.

Standard manufacturing lead time is 8 to 14 weeks from confirmed order, plus 2 to 6 weeks for international shipping depending on destination. Urgent orders can sometimes be expedited to 5–7 weeks at additional cost. Country-specific certification (EU CE, US FDA, ANVISA) may add 2 to 4 weeks.

Yes — the Closed Ampoule Filling and Sealing Machine is exported to 100+ countries across Asia, the Middle East, Africa, Europe, the Americas and Oceania. Lodha handles complete export documentation, packing, freight forwarding, customs liaison and on-site installation in the destination country. See the turnkey projects page for delivered references.

On-site installation, commissioning, IQ / OQ / PQ qualification, operator training and preventive maintenance are included for every Closed Ampoule Filling and Sealing Machine delivery. Remote troubleshooting is available 24/7 by phone, email and video. Spare parts are stocked at the Ahmedabad HQ and air-shipped within 5–7 working days to any export destination. A 12-month manufacturing warranty applies.